Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 480054 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Phycoerythrin |
Immunogen | NS0 mouse myeloma cell line transfected with human Histamine H1 R Met1-Ser487 Accession # AAH60802 |
Specificity | Detects human Histamine H1 R. Stains human Histamine H1 R transfectants but not irrelevant transfectants. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | HRH1 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light. |
Buffer | Supplied in a saline solution containing BSA and Sodium Azide. |
Preservative | Sodium Azide |
Histamine H1 R (HRH1) is a 60 kDa, 487 aa G-protein coupled 7-transmembrane putative glycoprotein. It is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues. Extracellular domains of human HRH1 share 72% aa sequence identity with corresponding regions of mouse or rat HRH1.
Secondary Antibodies |
Isotype Controls |
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