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GIPR Antibody (591853) [Phycoerythrin]

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HEK293 human embryonic kidney cell line transfected with either (A) human GIPR or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human GIPR PE-conjugated Monoclonal Antibody (Catalog # FAB8210P). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
591853
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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GIPR Antibody (591853) [Phycoerythrin] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human GIPR.
Met1-Cys466
Accession # P48546
Specificity
Detects human GIPR in direct ELISAs. Stains human GIPR transfected cells but not irrelevant transfectants in flow cytometry.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GIPR Antibody (591853) [Phycoerythrin]

  • gastric inhibitory polypeptide receptor
  • GIPR
  • GIP-R
  • Glucose-dependent insulinotropic polypeptide receptor
  • MGC126722
  • PGQTL2

Background

GIPR is a 7-transmembrane receptor for GIP (glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide). The 466 amino acid (aa) human GIPR contains 176 extracellular domain (ECD) aa that share 77% and 81% aa identity with mouse and rat GIPR ECD, respectively. A splice isoform of 430 aa has a deletion of aa 58-93 in the N-terminal ECD, while isoforms of 491 and 419 aa have alternate C-terminal cytoplasmic sequences. Engagement by GIP on pancreatic b‑cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose. GIPR is also expressed on adipocytes, osteoblasts and myelinating Schwann cell membranes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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