DHX58 Antibody [Alexa Fluor® 700]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 700

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Protocols & FAQs
Support & Research

DHX58 Antibody [Alexa Fluor® 700] Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human LGP2. The immunogen is located within amino acids 90 - 140 of LGP2. Amino Acid Squence: ALTSPEEEEHVELT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DHX58
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DHX58 Antibody [Alexa Fluor® 700]

  • D11lgp2e
  • D11LGP2probable ATP-dependent RNA helicase DHX58
  • DEXH (Asp-Glu-X-His) box polypeptide 58
  • EC 3.6.4.13
  • LGP2ortholog of mouse D11lgp2
  • Probable ATP-dependent helicase LGP2
  • Protein D11Lgp2 homolog
  • RIG-I-like receptor LGP2
  • RLR
  • RNA helicase LGP2

Background

Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interactswith DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, inparticuliar HCV RNA. Binding occurs at blunt dsRNA termini

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DHX58