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DHX58 Antibody [DyLight 755]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

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DHX58 Antibody [DyLight 755] Summary

Immunogen
Antibody was raised against a 11 amino acid synthetic peptide from near the center of human LGP2. The immunogen is located within amino acids 200 - 250 of LGP2. Amino Acid Squence: HRRSQDPFGDL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DHX58
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DHX58 Antibody [DyLight 755]

  • D11lgp2e
  • D11LGP2probable ATP-dependent RNA helicase DHX58
  • DEXH (Asp-Glu-X-His) box polypeptide 58
  • EC 3.6.4.13
  • LGP2ortholog of mouse D11lgp2
  • Probable ATP-dependent helicase LGP2
  • Protein D11Lgp2 homolog
  • RIG-I-like receptor LGP2
  • RLR
  • RNA helicase LGP2

Background

Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interactswith DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, inparticuliar HCV RNA. Binding occurs at blunt dsRNA termini

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DHX58