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Caspase-6 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-99463AF350
Alexa Fluor 405
NBP2-99463AF405
Alexa Fluor 488
NBP2-99463AF488
Alexa Fluor 532
NBP2-99463AF532
Alexa Fluor 594
NBP2-99463AF594
Alexa Fluor 647
NBP2-99463AF647
Alexa Fluor 700
NBP2-99463AF700
Alexa Fluor 750
NBP2-99463AF750
Allophycocyanin
NBP2-99463APC
CoraFluor 1
NBP2-99463CL1
DyLight 350
NBP2-99463UV
DyLight 405
NBP2-99463V
DyLight 488
NBP2-99463G
DyLight 550
NBP2-99463R
DyLight 594
NBP2-99463DL594
DyLight 650
NBP2-99463C
DyLight 680
NBP2-99463FR
DyLight 755
NBP2-99463IR
FITC
NBP2-99463F
HRP
NBP2-99463H
Janelia Fluor 525
NBP2-99463JF525
Janelia Fluor 549
NBP2-99463JF549
Janelia Fluor 646
NBP2-99463JF646
Janelia Fluor 669
NBP2-99463JF669
PE
NBP2-99463PE
PerCP
NBP2-99463PCP
Unconjugated
NBP2-99463-100ul
mFluor Violet 450 SE
NBP2-99463MFV450
mFluor Violet 500 SE
NBP2-99463MFV500
mFluor Violet 610 SE
NBP2-99463MFV610
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Caspase-6 Antibody [Biotin] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Caspase-6.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CASP6
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Alternate Names for Caspase-6 Antibody [Biotin]

  • Apoptotic protease Mch-2
  • CASP6
  • CASP-6
  • caspase 6, apoptosis-related cysteine peptidase
  • caspase 6, apoptosis-related cysteine protease
  • Caspase6
  • Caspase-6
  • EC 3.4.22
  • Mch2
  • MCH2EC 3.4.22.59

Background

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase-6 is a major apoptotic executioner (1,2). It exists as a pro-domain protein and is cleaved by caspase-3 into two active subunits, an 18 kDa and a 10 kDa subunit (3). Caspase-6 cleaves among many different intracellular proteins, nuclear lamins. Lamins play a significant role in maintaining the integrity of the cell membrane, and their cleavage results in subsequent cellular breakdown and death (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CASP6