Reactivity | All-NASpecies Glossary |
Applications | Flow, ICC/IF, IHC, ICC/IF |
Clone | 85-2C8 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Janelia Fluor 635 |
Immunogen | Bromodeoxyuridine/BrdU conjugated to hemocyanine (isolated from Helix pomatia) |
Localization | Nuclear |
Marker | Proliferation Marker |
Specificity | It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Developmental regulator Daam2 promotes glial cell tumors by degrading Von Hippel-Lindau protein By Jamshed Arslan Pharm.D. Glioblastoma is an aggressive type of cancer that forms from the star-shaped glial cells of the central nervous system, called astrocytes. Intriguingly, several genes linked to glioblasto... Read full blog post. |
BrDU (Bromodeoxyuridine) The thymidine synthetic nucleoside analogue bromodeoxyuridine (BrdU) has a long, colorful history of repeated use in molecular and cytokinetic studies, as detailed in reviews by Vanderlaan and Dolbeare (1,2). Because BrDU is only incorporated in... Read full blog post. |
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