Bordetella Pertussis Toxin Antibody (1280/204) [Janelia Fluor® 525] Summary
| Immunogen |
Native Bordatella pertussis toxin |
| Localization |
Secreted |
| Specificity |
NB100-64514 is reactive with Bordetella pertussis toxin in a simple ELISA. Reactivities with other organisms have not yet been determined. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Purity |
Protein A purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
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| Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark. |
| Buffer |
50mM Sodium Borate |
| Preservative |
0.05% Sodium Azide |
| Purity |
Protein A purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for Bordetella Pertussis Toxin Antibody (1280/204) [Janelia Fluor® 525]
Background
Pertussis toxin (islet-activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis, the organism that causes whooping cough. As revealed by polyacrylamide gel electrophoresis, the purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1. The A-protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B-oligomer, responsible for binding the toxin to the cell surface.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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