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ADAM8 Antibody (143338) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, CyTOF-ready, Flow
Clone
143338
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC10311U-100UG
Alexa Fluor 405
IC10311V-100UG
Alexa Fluor 488
IC10311G-100UG
Alexa Fluor 532
FAB10311X
Alexa Fluor 594
IC10311T-100UG
Alexa Fluor 647
IC10311R-100UG
Alexa Fluor 700
IC10311N-100UG
Alexa Fluor 750
IC10311S-100UG
Allophycocyanin
FAB10311A
Biotin
FAB10311B
DyLight 350
FAB10311D
DyLight 405
FAB10311E
DyLight 550
FAB10311L
DyLight 594
FAB10311M
DyLight 650
FAB10311W
DyLight 680
FAB10311Y
DyLight 755
FAB10311Z
FITC
FAB10311F
HRP
FAB10311H
Janelia Fluor 525
FAB10311JF525
Janelia Fluor 549
FAB10311I
Janelia Fluor 646
FAB10311J
Janelia Fluor 669
FAB10311JF669
PE
FAB10311P
PerCP
FAB10311C
Unconjugated
MAB10311
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10311
Carrier Free
MAB10311
Carrier Free
MAB10311-SP
Carrier Free
IC10311N-100UG
Carrier Free
IC10311G-100UG
Carrier Free
IC10311V-100UG
Carrier Free
IC10311U-100UG
Carrier Free
IC10311T-100UG
Carrier Free
IC10311S-100UG
Carrier Free
IC10311R-100UG
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ADAM8 Antibody (143338) [DyLight 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ADAM8 ectodomain
Asp158-Ser653
Accession # P78325
Specificity
Detects human ADAM8 in direct ELISAs and Western blots. Detects aa 498‑653 of rhADAM8, which corresponds to the cysteine-rich and EGF-like domains. In direct ELISAs, no cross-reactivity with recombinant human (rh) ADAM9, rhADAM10, rhADAM15, rhBACE, or rhTACE is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADAM8
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunoprecipitation
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ADAM8 Antibody (143338) [DyLight 488]

  • a disintegrin and metalloproteinase domain 8
  • ADAM 8
  • ADAM metallopeptidase domain 8
  • ADAM8
  • CD156a antigen
  • CD156a
  • CD156human leukocyte differentiation antigen
  • Cell surface antigen MS2
  • EC 3.4.24
  • EC 3.4.24.-
  • MGC134985
  • MS2
  • MS2disintegrin and metalloproteinase domain-containing protein 8

Background

Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADAM8