PKM2 Products

Description

PKM2 is encoded by this gene is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Bioinformatics

Entrez	100008676 Rabbit 18746 Mouse 5315 Human
Uniprot	AAH07640 Human AAH07640.1 Human AAH35198 Human NM_002654 Human NP_002645 Human NP_002645.3 Human NP_872270 Human NP_872271 Human P14618 Human P14786 Human P52480 Mouse
Product By Gene ID	5315
Alternate Names	CTHBP Cytosolic thyroid hormone-binding protein MGC3932 OIP-3 OIP3EC 2.7.1.40 Opa-interacting protein 3 PK, muscle type PK2 PK3PKM Pyruvate kinase 2/3 pyruvate kinase isozymes M1/M2 Pyruvate kinase muscle isozyme pyruvate kinase, muscle TCB THBP1p58 Thyroid hormone-binding protein 1 thyroid hormone-binding protein, cytosolic Tumor M2-PK

Research Areas for PKM2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism

Related PKM2 Blog Posts

Check out the latest blog posts on PKM2.

5 Stars for the PKM2 Antibody Novus' Pyruvate Kinase M2 antibody (cat # NBP1-48308) has received some glowing product reviews and customer feedback lately. One satisfied customer wrote, "The best thing about this antibody is that it works well for immunofluorescence staining of fr...    Read more.

MAPK3/ERK1 - A signal transduction pathway with roles in development and disease Mitogen-activated protein kinases (MAPKs) are important signaling proteins needed to transmit and relay extracellular stimuli and to illicit intracellular responses (1). The MAPK family of proteins are serine/threonine kinases that are able to phos...    Read more.

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