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Mucosal Tolerance Induction Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Mucosal Tolerance Induction Pathway and Allergy, Autoimmune Reaction, Autoimmune Diseases, Inflammation, Decreased Immunologic Activity [pe]. The study of the Mucosal Tolerance Induction Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Mucosal Tolerance Induction Pathway has been researched in relation to Tolerance Induction, Sensitization, Immune Response, Cytokine Production, Hypersensitivity. The Mucosal Tolerance Induction Pathway complements our catalog of research reagents including antibodies and ELISA kits against OVALBUMIN, GM-CSF, CD4, CD8A, CHI3L1.

Top Research Reagents

We have 6726 products for the study of the Mucosal Tolerance Induction Pathway that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NB100-39002
Immunohistochemistry-Paraffin: FoxP3 Antibody [NB100-39002] - Mouse spleen stained with FoxP3 antibody. IHC-P image submitted by a verified customer review.Immunohistochemistry-Paraffin: FoxP3 Antibody [NB100-39002] - Number of Granzyme B+ and FoxP3+ cells infiltrating tumors. Representative images of IHC staining of FoxP3+ and Granzyme B+ cells in the peri-tumoral areas in two mice characterized by low FoxP3+ and high Granzyme B+ (panels 1 and 2) or high FoxP3+ and low Granzyme B+ (panels 3 and 4). Image collected and cropped by Citeab from the following publication (Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting. Oncotarget (2018) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, IB

     2 Reviews

62 Publications
NBP1-49045
Flow Cytometry: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of lymph nodes by multiple staining.Immunohistochemistry-Paraffin: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - CD8 alpha expression in mouse spleen tissue using anti-CD8 alpha antibody. Image from verified customer review.

Rat Monoclonal
Species Mouse, Rat
Applications Flow, ICC/IF, IHC

     3 Reviews

28 Publications
NBP1-72042
Western Blot: Doublecortin Antibody [NBP1-72042] - staining of Mouse fetal Brain lysate (35 ug protein in RIPA buffer). Antibody at 0.01 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: Doublecortin Antibody [NBP1-72042] - Immunofluorescence analysis of paraformaldehyde fixed KNRK cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

5 Publications
AF2254
DNER was detected in perfusion fixed frozen sections of mouse brain (cerebellum) using Goat Anti-Mouse DNER Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2254) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=DNER does not activate, function with, or bind to Notch, but known Notch ligand DLL1 does.(A) Pooled luciferase results from 4 separate experiments (normalized to the mean of empty vector in each experiment). U2OS cells were transfected with ligand (DLL1, DNER, or EV), and separately a population of U2OS cells was transfected to express Notch, the control luciferase Renilla, and TP1, a promoter that expresses firefly luciferase when Notch is activated. The two populations were co-cultured 24 hours after transfection (trans configuration), and activity read after an additional 24–48 hours of incubation. (B) C2C12 cells (myoblasts) were incubated with differentiation media (2% horse serum) that either had pre-clustered DLL1-fc (1:1), pre-clustered DNER-fc (1:1), un-clustered DNER-fc, or fc only, all at a ratio of 1:150 in media. Cells were incubated for 72 hours, then fixed, and stained for the presence of myosin heavy chain (MHC) and nuclei. By measuring the percent of total nuclei that were inside of differentiated MHC positive myotubes, fusion indexes were calculated. (C) DNER (top left, green) transfected U2OS cells were not labeled by pre-clustered Notch-fc (top middle, red) but DLL1 (bottom left, green) transfected U2OS cells were labeled by pre-clustered Notch-fc (bottom middle, red). Merged images are shown at far right. Scale 10 μM. **** = p value <0.0001. *** = p value 0.002. ns = not significant. DLL1 = Delta-like 1, a known Notch Ligand, DNER = Delta/Notch-like epidermal growth factor (EGF) related receptor, GSI =  gamma -secretase inhibitor, fc only = rabbit anti-human-fc. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0161157), licensed under a CC-BY license. Not internally tested by R&D Systems.

Goat Polyclonal
Species Mouse
Applications WB, IHC

12 Publications
AF-492-NA
Recombinant Mouse CXCL9/MIG (Catalog #<br><a class=mTORC1 regulates Cxcl9 in osteoblasts.(a) Representative images of in situ hybridization of Cxcl9 mRNA in conjunction with immunostaining of Runx2 in femur sections of 12-week-old male mice bone. Boxed area is enlarged in the bottom right corner. Cxcl9+ osteoblasts out of total osteoblasts were also quantified. Scale bar, 50 μm. n=9 per group. (b) Representative photomicrographs of immunostaining of CXCR3 in CD31+ ECs in bone marrow and quantitative analysis of CXCR3+ ECs out of total ECs in 12-week-old male mice bone. Scale bar, 50 μm. n=9 per group. (c) Representative photomicrographs of immunostaining of CXCR3 in cultured HUVECs. Scale bar, 100 μm. (d) Cxcl9 concentrations assessed by ELISA in bone marrow (BM) and serum. n=5 per group. (e) Quantitative PCR analysis of Cxcl9 mRNA in primary osteoblasts. (f) Western blot of Cxcl9 in primary osteoblasts. (g) Concentrations of Cxcl9 in CM of primary osteoblasts assessed by ELISA. n=5 per group. Data are shown as mean±s.d. *P<0.05, **P<0.01 (Student's t-test). Ctrl, control. Image collected and cropped by CiteAb from the following open publication (https://www.nature.com/articles/ncomms13885), licensed under a CC-BY license. Not internally tested by R&D Systems.

Goat Polyclonal
Species Mouse
Applications ELISA(Cap), ELISA(Det), Neut

31 Publications
7754-BH/CF
Recombinant human TGF-beta 1 (<a class=NoLineLink href=


Species Human
Applications BA

53 Publications
6507-IL/CF
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 0.05-0.2 ng/mL.


Species Human
Applications BA

3 Publications
DC3L10
N/A Chitinase 3-like 1/YKL-40 [HRP]N/A Chitinase 3-like 1/YKL-40 [HRP]


Species Human
Applications ELISA

38 Publications
DR2A00
N/A CD25/IL-2R alpha [HRP]N/A CD25/IL-2R alpha [HRP]


Species Human
Applications ELISA

36 Publications
M5000
N/A IL-5 [HRP]N/A IL-5 [HRP]


Species Mouse
Applications ELISA

92 Publications
285-IF
Recombinant Human IFN-gamma (Catalog # 285-IF) has a molecular weight (MW) of 34.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).1 μg/lane of Recombinant Human IFN-gamma  was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.


Species Human
Applications BA

     2 Reviews

453 Publications
DY417
N/A IL-10 [Biotin]


Species Mouse
Applications ELISA

302 Publications
DY413
N/A IL-13 [Biotin]


Species Mouse
Applications ELISA

149 Publications
NBP1-19371
Immunohistochemistry: CD4 Antibody [NBP1-19371] - Increased CD3+ and CD4+ T-cell occurrence in the brainstem of SHR-72 transgenic rat model for tauopathies. (A-D) Immunofluorescence staining showed CD4+ T-cells in SHR-72 transgenic animals. (E- H) Immunofluorescence staining showed more perivascular than brain parenchyma infiltrating CD4+ T-cells in SHR-72 transgenic animals. PLoS One. 2019 May 23;14(5):e0217216. doi: 10.1371/journal.pone.0217216.Immunohistochemistry: CD4 Antibody [NBP1-19371] - DBZ inhibits the accumulation of CD4+ T cells and Th2 differentiation in the AAAs. (B) The representation of immunohistochemical staining for CD4+ in abdominal aorta from four groups (left). Bar graphs show the percentage of CD4+ positive cell areas (right; n=3 per group). Bar: 50 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     9 Reviews

50 Publications
NB600-717
Western Blot: MBP Antibody (12) [NB600-717] - Mouse Brain Tissue lysate probed with Rat anti MBP.Immunocytochemistry/Immunofluorescence: MBP Antibody (12) [NB600-717] - Histological and mRNA analysis of the inflammatory cytokines in the vehicle- or etifoxine-treated mice at onset of clinical symptoms. At day 10 p.i., drug treated animals showed significant differences in MBP staining. Animals treated with etifoxine showed an increase in retention of percentage of MBP coverage (*p = 0.001).  Image collected and cropped by CiteAb from the following publication (https://embomolmed.embopress.org/cgi/doi/10.1002/emmm.201202124), licensed under a CC-BY license.

Rat Monoclonal
Species Bovine
Applications WB, ELISA, ICC/IF

     3 Reviews

42 Publications
H00003669-M01
Western Blot: ISG20 Antibody (1B2-3C9) [H00003669-M01] - BT-474, HCC1954 and SUM190 whole cell lysates were loaded with 40 ug/lane. 10% SDS-PAGE. ISG20 Antibody (H00003669-M01) was used for primary antibody: 1:1000, 4C, overnight. WB image submitted by a verified customer review.Immunocytochemistry/Immunofluorescence: ISG20 Antibody (1B2-3C9) [H00003669-M01] - Analysis of monoclonal antibody to ISG20 on HeLa cell . Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     1 Review

2 Publications
NBP3-07388
Immunohistochemistry-Paraffin: EPX Antibody (rEPO104) [NBP3-07388] - Formalin-fixed, paraffin-embedded human Pancreas stained with EPX Recombinant Mouse Monoclonal Antibody (rEPO104).

Mouse Monoclonal
Species Human
Applications Flow, ICC/IF, IHC

NBP3-11412

Mouse Monoclonal
Species Sheep
Applications WB, ELISA, IHC

5 Publications