Species: Hu, Mu
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, RM
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Simple Western
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
Lactoylglutathione lyase, also known as GLO1, is a member of the glyoxalase I family that is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. It is believed that inactivation of GLO1 in endothelial cells contributes to vascular complications in diabetes. GLO1 has also been shown to extend lifespan in C. elegans, and has been shown to be upregulated in malignant cells.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
2739 |
| Alternate Names |
- Aldoketomutase
- EC 4.4.1.5
- GLOD1
- Glx I
- GLYI
- glyoxalase domain containing 1
- glyoxalase Ialdoketomutase
- Ketone-aldehyde mutase
- lactoyl glutathione lyase
- lactoylglutathione lyase
- Methylglyoxalase
- methylglyoxalase
- S-D-lactoylglutathione methylglyoxal lyase
|
![Western Blot Glyoxalase I Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Glyoxalase_I_AF4959_Western_Blot_5588.jpg)
![Simple Western Glyoxalase I Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Glyoxalase_I_AF4959_Simple_Western_16747.jpg)
