DNMT3B Products

Description

DNA (cytosine-5)-methyltransferase 3B (DNAMT3b) is a C5-methyltransferase family member that is required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development.

Improper methylation patterns have been linked to certain human tumors and developmental abnormalities. DNMT3b antibodies are useful tools for DNA methlyation research and studies on certian cancer.

Bioinformatics

Entrez	13436 Mouse 1789 Human
Uniprot	NP_008823 Human O88509 Mouse Q9UBC3 (human) Human Q9UBC3 Human Q9UBC3-3 Human
Product By Gene ID	1789
Alternate Names	DNA (cytosine-5-)-methyltransferase 3 beta DNA (cytosine-5)-methyltransferase 3B DNA methyltransferase HsaIIIB DNA MTase HsaIIIB Dnmt3b EC 2.1.1.37 ICF M.HsaIIIB

Research Areas for DNMT3B

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Modifiers
Chromatin Research
DNA Methyltransferases
DNA Repair
Epigenetics

Related DNMT3B Blog Posts

Check out the latest blog posts on DNMT3B.

The role of DNMT3A in development Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.

Not as Pluripotent as You Used to Be: Embryonic Stem Cell Markers and the Aging Process We at Novus Biologicals recently extended our antibody catalog to include several embryonic stem cells (ESC) antibodies validated for use in FACS (fluorescent activated cell sorting) assays. Among them was Oct4, which recently became the focus of an i...    Read more.

DNMT3B: Roles in Leukemia DNA-methyltransferase 3B (DNMT3B), also known as DNA methyltransferase HsaIIIB, is a member of the class I-like SAM-binding methyltransferase superfamily and C5-methyltransferase family. DNMT3B plays an essential role in the establishment of DNA methy...    Read more.

Controlling Epigenetic Signaling with Dnmt1 and Dnmt3b Dnmt1 belongs to the C5-methyltransferase family that repairs cytosines in dsDNA using a nucleophilic attack mechanism. Dnmt1 is the most abundant mammalian DNA methyltransferase. It is the key methylation maintenance enzyme for both DNA replication/r...    Read more.

Go Ahead! Make My DNA DNA methylation plays a critical role the long-term silencing of transcription and is essential for processes such as embryonic development, germline differentiation, and tissue maturation. Dnmt3a is a member of the C5-methyltransferase family that re...    Read more.

Eat responsibly: Epigenetic downregulation of Ankrd26 gene by long-term high-fat intake promotes obesity and inflammation By Jamshed Arslan Pharm.D. White adipose tissue (WAT) represents the primary site to store energy in humans. WAT’s endocrine regulation of energy balance is controlled by nutritional status, exercise, and hormones l...    Read more.

Read more DNMT3B related blogs.