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Septo-optic Dysplasia: Disease Bioinformatics

Research of Septo-optic Dysplasia has been linked to Dysplasia, Pituitary Diseases, Hypoplasia, Hypopituitarism, Optic Nerve Hypoplasia. The study of Septo-optic Dysplasia has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Septo-optic Dysplasia include Pathogenesis, Secretion, Brain Development, Pituitary Gland Development, Gland Development. These pathways complement our catalog of research reagents for the study of Septo-optic Dysplasia including antibodies and ELISA kits against GROWTH HORMONE, AVP, GH1, GHRH, HES1.

Top Research Reagents

We have 1731 products for the study of Septo-optic Dysplasia that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Lhx4 Antibody
NBP3-38503
Western Blot: Lhx4 Antibody [NBP3-38503] - Western blot analysis of various lysates using Lhx4 Rabbit pAb at 1:1000 dilution.<br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.Immunohistochemistry: Lhx4 Antibody [NBP3-38503] - Immunohistochemistry analysis of paraffin-embedded Mouse cancer using Lhx4 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

SLC20A1 Antibody
NBP1-32252
Western Blot: SLC20A1 Antibody [NBP1-32252] - Unboiled U87-MG cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SLC20A1 antibody [N3C2], Internal diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)Immunohistochemistry-Paraffin: SLC20A1 Antibody [NBP1-32252] - Paraffin-embedded mouse mammary gland. SLC20A1 antibody [N3C2], Internal diluted at 1:500.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

HES-1 Antibody (OTI4H1)
NBP1-47791
Western Blot: HES-1 Antibody (OTI4H1) [NBP1-47791] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1 (1:500).Immunocytochemistry/Immunofluorescence: HES-1 Antibody (OTI4H1) [NBP1-47791] - HeLa cells using anti-HES1 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

8 Publications
HESX1 Antibody
NBP1-89090
Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts as well as in Leydig cells.Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human skeletal muscle shows no nuclear positivity in striated muscle fibers as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

gamma-glutamyl hydrolase Antibody
NBP1-90927
Western Blot: gamma-glutamyl hydrolase Antibody [NBP1-90927] - Analysis in control (vector only transfected HEK293T lysate) and GGH over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: gamma-glutamyl hydrolase Antibody [NBP1-90927] - Staining of human skeletal muscle shows very weak cytoplsmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
Pit1 Antibody
NBP1-92273
Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human liver, pancreas, pituitary gland and tonsil using Anti-POU1F1 antibody NBP1-92273 (A) shows similar protein distribution across tissues to independent antibody NBP2-55357 (B).Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human pituitary gland shows moderate to strong nuclear positivity in neuroendocrine cells in the anterior lobe.

Rabbit Polyclonal
Species Human, Mouse
Applications IHC, IHC-P

17 Publications
SOD1/Cu-Zn SOD Antibody
NBP2-24915
Western Blot: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Bovine ocular fluid. Antibody at 1:1000. Western blot image submitted by a verified customer review.Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Analysis of Superoxide Dismutase 1 in FFPE human liver tissue using an isotype control (top) and NBP2-24915 (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     3 Reviews

21 Publications
POMC Antibody
NB100-1533
Immunohistochemistry: POMC Antibody [NB100-1533] - Representative confocal images of POMC in POMC-transfected WT and Sel1L-/- N2a cells. White arrows point to POMC-containing secretory granules, while yellow arrows point to perinuclear POMC. KDEL marks the ER. Representative data from at least 2 independent experiments are shown. Image collected and cropped by CiteAb from the following publication (jci.org/articles/view/96420), licensed under a CC-BY license.Flow Cytometry: POMC Antibody [NB100-1533] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

10 Publications
Thyrotropin Releasing Hormone Antibody
NBP2-34014
Immunohistochemistry-Paraffin: Thyrotropin Releasing Hormone Antibody [NBP2-34014] - Analysis in human cervix, uterine and skeletal muscle tissues. Corresponding TRH RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Thyrotropin Releasing Hormone Antibody [NBP2-34014] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Neurophysin II/Arg-vasopressin Antibody [Unconjugated]
AF009
Neurophysin II was detected in immersion fixed paraffin-embedded sections of human pituitary using Goat Anti-Human Neurophysin II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF009) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (<a class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC

Growth Hormone Antibody [Unconjugated]
AF1067
Western blot shows lysates of human, mouse, and rat pituitary gland tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human Growth Hormone Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1067) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Growth Hormone was detected in immersion fixed paraffin-embedded sections of human pituitary using Goat Anti-Human/Mouse/Rat Growth Hormone Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1067) at 10 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

15 Publications
Prolactin Antibody [Unconjugated]
AF1445
Western blot shows lysates of mouse pituitary tissue and rat pituitary tissue. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse/Rat Prolactin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1445) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=Recombinant Mouse Prolactin (<a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, Simple Western, IHC

7 Publications
SOX3 Antibody [Unconjugated]
AF2569
SOX3 was detected in immersion fixed NTera-2 human testicular embryonic carcinoma cell line differentiation with retinoic acid using Goat Anti-Human SOX3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2569) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green, upper panel; <a class=SOX3 was detected in immersion fixed U‑251 MG human glioblastoma cells (positive) and absent in HDLM‑2 human Hodgkin’s lymphoma cells (negative) using Goat Anti-Human SOX3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2569) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, ICC

13 Publications
SOX2 Antibody [Unconjugated]
AF2018
Western blot shows lysates of D3 mouse embryonic stem cell line, NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX2/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) or control antibody (<a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

     6 Reviews

371 Publications
IGF-I/IGF-1 [Unconjugated]
291-G1
Recombinant Human IGF-I/IGF-1 (Catalog # 291-G1) stimulates proliferation in the MCF-7 human breast cancer cell line. The ED<sub>50</sub> for this effect is 0.3‑1.5 ng/mL.1 μg/lane of Recombinant Human IGF-I/IGF-1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.


Species Human
Applications BA

224 Publications
GHRH Antibody - Azide and BSA Free
NBP3-04850
Western Blot: GHRH Antibody [NBP3-04850] - Western blot analysis of extracts of various cell lines, using GHRH antibody (NBP3-04850) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

PROP1 Antibody
NBP3-10488
Western Blot: PROP1 Antibody [NBP3-10488] - Western blot analysis using NBP3-10488 on Human COLO205 as a positive control. Antibody Titration: 0.2-1 ug/ml

Rabbit Polyclonal
Species Human
Applications WB

GATD3A Antibody (1F5)
H00008209-M01
Western Blot: C21orf33 Antibody (1F5) [H00008209-M01] - C21orf33 monoclonal antibody (M01), clone 1F5 Analysis of C21orf33 expression in HeLa.Immunocytochemistry/Immunofluorescence: C21orf33 Antibody (1F5) [H00008209-M01] - Analysis of monoclonal antibody to C21orf33 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

LHX3 Antibody
NBP3-13352
Western Blot: LHX3 Antibody [NBP3-13352] - Rat tissue extract (50 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with LHX3 antibody (NBP3-13352) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: LHX3 Antibody [NBP3-13352] - LHX3 antibody detects LHX3 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: LHX3 stained by LHX3 antibody (NBP3-13352) diluted at 1:500. Red: Tau, stained by Tau antibody [GT287] diluted at 1:500. Blue: Fluoroshield with DAPI.

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, ICC/IF, IHC


Related Genes

Septo-optic Dysplasia has been researched against:

Related Pathways

Septo-optic Dysplasia has been linked to:

Related Diseases

Septo-optic Dysplasia has been studied in relation to diseases such as:

Related PTMs

Septo-optic Dysplasia has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Septo-optic Dysplasia is also known as De Morsier Syndrome, Septo-optic Dysplasia Sequence, Septo-optic Dysplasia With Growth Hormone Deficiency, Septooptic Dysplasia.