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Hypotrichosis: Disease Bioinformatics

Research of Hypotrichosis has been linked to Dysplasia, Ectodermal Dysplasia, Hypohidrosis, Hypodontia, Developmental Absence Of Tooth. The study of Hypotrichosis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hypotrichosis include Pathogenesis, Anagen, Telogen, Hair Cycle, Hair Follicle Morphogenesis. These pathways complement our catalog of research reagents for the study of Hypotrichosis including antibodies and ELISA kits against HAIRLESS, P-CADHERIN, XLHED, CDH3, CDH15.

Top Research Reagents

We have 975 products for the study of Hypotrichosis that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Plakophilin 1 Antibody
NBP1-90042
Immunohistochemistry-Paraffin: Plakophilin 1 Antibody [NBP1-90042] - Staining in human skin and skeletal muscle tissues using anti-PKP1 antibody. Corresponding PKP1 RNA-seq data are presented for the same tissues.Western Blot: Plakophilin 1 Antibody [NBP1-90042] - Analysis in human cell lines PC-3 and A-549 using anti-PKP1 antibody. Corresponding PKP1 RNA-seq data are presented for the same cell lines. Loading control: anti-PPIB.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

1 Publication
P-Cadherin Antibody [Unconjugated]
AF761
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=P-Cadherin was detected in immersion fixed A431 human epithelial carcinoma cell line using Goat Anti-Mouse P-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF761) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; <a class=

Goat Polyclonal
Species Mouse
Applications WB, Simple Western, Flow

     1 Review

26 Publications
M-Cadherin/Cadherin-15 Antibody [Unconjugated]
AF4096
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human M-Cadherin/Cadherin-15 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4096) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=C2C12 mouse myoblast cell line was stained with Sheep Anti-Human M‑Cadherin/<BR>Cadherin‑15 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4096, filled histogram) or control antibody (Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

3 Publications
Desmocollin-3 Antibody (765129)
MAB7265
Western blot shows lysates of mouse skin tissue and mouse embryo (15 d.p.c.) tissue. PVDF membrane was probed with 1 µg/mL of Rat Anti-Mouse Desmocollin-3 Monoclonal Antibody (Catalog # MAB7265) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # <a class=Desmocollin-3 was detected in perfusion fixed frozen sections of mouse embryo (15 d.p.c.) using Rat Anti-Mouse Desmocollin-3 Monoclonal Antibody (Catalog # MAB7265) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Rat Monoclonal
Species Mouse
Applications WB, IHC

     1 Review

Hairless Antibody [Unconjugated]
AF5708
Hairless was detected in immersion fixed human NHEK epidermal keratinocytes using 10 µg/mL Goat Anti-Human Hairless Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5708) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=Western blot shows lysates of HEK293 human embryonic kidney cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Hairless Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5708) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, ICC

1 Publication
Matriptase/ST14 Antibody [Unconjugated]
AF3946
PC‑3 human prostate cancer cell line was stained with Sheep Anti-Human Matriptase/ST14 Catalytic Domain Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF3946, filled histogram) or control antibody (Catalog # <A class=NoLineLink href=Zymogen-locked matriptase induces epidermal prostasin processing. Protein extracts from skin (a), kidney (b), lung (c), and intestine (d) from newborn St14zym/zym (lanes 1 and 2), St14+/+ (lanes 3 and 4), and St14–/– (lane 5) littermates were separated by capillary electrophoresis and probed with antibodies against matriptase (top panels), prostasin (middle panels), or beta -actin (bottom panels). Lanes 6 and 7 in (a) are skin extracts from prostasin null (Prss8–/–) and prostasin zymogen-locked (Prss8zym/zym) mice, respectively. Zymogens of matriptase and prostasin are indicated with filled arrows, and the activated forms are indicated with open arrows. n.s. non-specific. Positions of molecular weight markers (kDa) are indicated on the left. e Representative example of quantification of activated prostasin (open arrow) and zymogen prostasin (filled arrows) in protein extracts from skin from a newborn St14zym/zym mouse (top panel), St14+/+ mouse (second panel from top), and a newborn St14–/– mouse (second panel from bottom). Skin extracts from a newborn mouse expressing zymogen-locked (Prss8zym/zym) endogenous prostasin is included as reference (bottom panel). f Ratio of activated prostasin to total prostasin in skin extracts from newborn St14zym/zym (left bar, n = 7), St14+/+ (middle bar, n = 7), and St14–/– (right bar, n = 2) mice, quantified as in (e). Data are shown as mean ± SD. *P = 0.0011 was determined by one-way ANOVA, two-tailed. Additional file 1: Raw supporting data Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28571576), licensed under a CC-BY license. Not internally tested by R&D Systems.

Sheep Polyclonal
Species Human
Applications WB, CyTOF-ready, ICFlow

19 Publications
SOX18 Antibody
AF5077
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, HUVEC human umbilical vein endothelial cells, and K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 1 µg/mL of Human SOX18 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5077) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB

Corneodesmosin Antibody [Unconjugated]
AF5725
Corneodesmosin was detected in immersion fixed paraffin-embedded sections of human skin using Sheep Anti-Human Corneodesmosin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5725) at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications IHC

3 Publications
Desmoglein-4 Antibody
AF6589
Western blot shows lysates of human skin tissue. PVDF Membrane was probed with 0.1 µg/mL of Human Desmoglein-4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6589) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB

1 Publication
Desmoglein-1 Antibody [Unconjugated] - Propeptide
AF944
Desmoglein-1 was detected in immersion fixed paraffin-embedded sections of human skin using Goat Anti-Human Desmoglein-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF944) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IHC

4 Publications
EDA-A1/Ectodysplasin A1
3944-ED


Species Human
Applications Bind

4 Publications
LPAR6/P2RY5 Antibody - BSA Free
NLS850
Immunohistochemistry-Paraffin: LPAR6/P2RY5 Antibody [NLS850] - Brain, cortex, neuronImmunohistochemistry-Paraffin: LPAR6/P2RY5 Antibody [NLS850] - Analysis of anti-LPAR6 / P2RY5 / P2Y5 antibody with human thymus.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

LPAR4/LPA4 Antibody - BSA Free
NLS1895
Immunohistochemistry-Paraffin: P2Y9 Antibody [NLS1895] - Human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunohistochemistry-Paraffin: P2Y9 Antibody [NLS1895] - Analysis of anti-LPAR4 / GPR23 antibody with kidney at 2 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications Flow, IHC, IHC-P

APCDD1 Antibody - BSA Free
NB110-92756
Western Blot: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 knockdown potently (C) inhibited cell proliferation. Error bars represent mean +/- SD of three replicates (*P < 0.05, **P < 0.01, ***P < 0.001). (E) A673 and SKNMC cells stably expressing shMEIS1 were transiently transfected with plasmid encoding APCDD1, and subjected to immunoblotting and MTT assays. Bars represent mean +/- SD of three replicates (**P < 0.01). Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/nar/article/47/3/1255/5212009) licensed under a CC-BY license.Western Blot: APCDD1 Antibody [NB110-92756] - Detection of APCDD1 in human heart lysate

Rabbit Polyclonal
Species Human, Mouse, Chicken
Applications WB, KD

2 Publications
LIPH Antibody - Azide and BSA Free
NBP3-03946
Western Blot: LIPH Antibody [NBP3-03946] - Analysis of extracts of various cell lines, using LIPH antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

LIPC Antibody - BSA Free
NBP3-04922
Immunocytochemistry/Immunofluorescence: LIPC Antibody [NBP3-04922] - Analysis of A549 cells using LIPC antibody . Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF