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Complete Trisomy 18 Syndrome: Disease Bioinformatics

Research of Complete Trisomy 18 Syndrome has been linked to Trisomy, Down Syndrome, Cytogenetic Abnormality, Patau Syndrome, Aneuploidy. The study of Complete Trisomy 18 Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Complete Trisomy 18 Syndrome include Interphase, Meiosis, Pathogenesis, Metaphase, Meiosis Ii. These pathways complement our catalog of research reagents for the study of Complete Trisomy 18 Syndrome including antibodies and ELISA kits against AFP, TRIM26, PAPPA, NTM, NTS.

Top Research Reagents

We have 2172 products for the study of Complete Trisomy 18 Syndrome that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

MEFV Antibody
NB600-809
Immunocytochemistry/Immunofluorescence: MEFV Antibody [NB600-809] - Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Flow Cytometry: MEFV Antibody [NB600-809] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human
Applications Flow, ICC/IF, PEP-ELISA

1 Publication
Bcl-2 Antibody
NB100-56098
Western Blot: Bcl-2 Antibody [NB100-56098] - Analysis of Bcl-2 in whole cell lysate from Daoy cells. Cells were transfected with (1) scrambled control siRNA or (2) Bcl-2 siRNA. Image from verified customer review.Western Blot: Bcl-2 Antibody [NB100-56098] - EA reduced MPP+-induced dopaminergic neuronal apoptosis by increasing BDNF (brain-derived neurotrophic factor) expression and further Akt phosphorylation in the rat substantia nigra. Eight days after MPP+ administration, our Western blot results (MAB7566) show that MPP+ treatment reduced tyrosine hydroxylase and Bcl-2 expression in the ipsilateral side of the rat substantia nigra (SN), but not in the contralateral side. EA stimulation (50 Hz) enhanced mature BDNF, tyrosine hydroxylase, and Bcl-2 expression in the MPP+-treated ipsilateral side. Image collected and cropped by CiteAb from the following publication (https://www.mdpi.com/1422-0067/18/9/1846), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     2 Reviews

26 Publications
Recombinant Human CGB5 GST (N-Term) Protein
H00093659-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

SP1 Antibody
NB600-232
Western Blot: SP1 Antibody [NB600-232] - Detection of Human SP1 by Western Blot. Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Affinity purified rabbit anti-SP1 antibody (NB600-232) used for WB at 0.04 ug/mL. Detection by chemiluminescence with an exposure time of 3 minutes.Immunohistochemistry-Paraffin: SP1 Antibody [NB600-232] - FFPE sections of human breast carcinoma (left) and mouse squamous cell carcinoma (right). Affinity purified rabbit anti-Sp1 used at a dilution of 1:1,000 (1 ug/mL). Detection by DAB.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

7 Publications
Neurotensin Antibody
NBP2-33903
Immunohistochemistry-Paraffin: Neurotensin Antibody [NBP2-33903] - Analysis in human small intestine and skeletal muscle tissues. Corresponding NTS RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Neurotensin Antibody [NBP2-33903] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Neurotrimin/HNT Antibody [Unconjugated]
AF1235

Goat Polyclonal
Species Human
Applications WB, IHC

2 Publications
Pappalysin-1/PAPP-A Antibody [Unconjugated]
AF2487
Western blot shows lysate of human pregnant sera. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human Pappalysin-1/PAPP-A Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2487) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IP

5 Publications
IL-31RA Antibody [Unconjugated]
AF2769
U937 human histiocytic lymphoma cell line was stained with Goat Anti-Human IL‑31 RA Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF2769, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=IL-31 RA was detected in immersion fixed K562 human chronic myelogenous leukemia cell line using Goat Anti-Human IL-31 RA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2769) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

4 Publications
alpha-Fetoprotein/AFP Antibody (189502) [Unconjugated]
MAB1368
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse a-Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=a-Fetoprotein/AFP was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Mouse Anti-Human/Mouse a-Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1368) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Simple Western, CyTOF-ready

     3 Reviews

89 Publications
Chorionic Gonadotropin alpha Chain (hCG alpha) Antibody (381012)
MAB4169
Chorionic Gonadotropin, a Chain (a HCG) was detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human Chorionic Gonadotropin, a Chain (a HCG) Monoclonal Antibody (Catalog # MAB4169) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC

PSG1 [HRP]
DPSG10
N/A PSG1 [HRP]N/A PSG1 [HRP]


Species Human
Applications ELISA

2 Publications
COCO/DAND5 [Unconjugated]
3047-CC


Species Human
Applications BA

4 Publications
SLPI [HRP]
DPI00
N/A SLPI [HRP]N/A SLPI [HRP]


Species Human
Applications ELISA

36 Publications
PLGF [HRP]
DPG00
N/A PLGF [HRP]N/A PLGF [HRP]


Species Human
Applications ELISA

79 Publications
TRIM26 Antibody
NBP2-47594
Immunocytochemistry/Immunofluorescence: TRIM26 Antibody [NBP2-47594] - Staining human cell line A-431 shows positivity in cytoplasm and nucleus but excluded from the nucleoli.Immunohistochemistry-Paraffin: TRIM26 Antibody [NBP2-47594] - Staining of human tonsil shows strong cytoplasmic positivity in germinal center and non-germinal center cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

5'-Nucleotidase/CD73 Antibody (AD2) - BSA Free
NBP2-48480
Immunohistochemistry-Paraffin: 5'-Nucleotidase/CD73 Antibody (AD2) [NBP2-48480] - Analysis of 5'-Nucleotidase/CD73 antibody on Human lung tissue. PFA fixed paraffin-embedded sections. Sections were incubated with the primary antibody overnight in 4C (1:200 dilution). Image from verified customer review.Flow Cytometry: 5'-Nucleotidase/CD73 Antibody (AD2) [NBP2-48480] - A surface stain was performed on CD3+ human peripheral blood lymphocytes with CD73 (AD2) antibody NBP2-48480AF488 and a matched isotype control NBP2-27287AF488. Cells were incubated in an antibody dilution of 10 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-25186PCP.

Mouse Monoclonal
Species Human
Applications Flow, IHC, IHC-Fr

     1 Review

15 Publications
MALT1 Antibody
NB100-56158
Western Blot: MALT1 Antibody - Unpurified [NB100-56158] - Analysis of MALT1/Paracaspase expression using this antibody. HEK293N cells transiently transfected with control (empty) plasmid (Ctl-) or human full-length MALT1 (Ctl+) were used as negative or positive controls, respectively. Freshly isolated human polymorphonuclear neutrophils (PMN) and resting B-cells were negative. MALT1 expression was detected in SKW64, Ramos, and BJAB B-cell lymphoma lines, and 3 out of 6 B-cell chronic lymphocytic luekemia (CLL) patients.Immunohistochemistry-Paraffin: MALT1 Antibody - Unpurified [NB100-56158] - Analysis of MALT1/Paracaspase expression in formalin-fixed human reactive lymph node using this antibody at 1:2000. A) Low magnification A1-A3) high magnification from A. A1) mantle zone A2) germinal center A3) marginal zone. Hematoxylin-eosin counterstain.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

GGT1 Antibody (1F9)
H00002678-M01
Western Blot: GGT1 Antibody (1F9) [H00002678-M01] - GGT1 monoclonal antibody (M01), clone 1F9 Analysis of GGT1 expression in NIH/3T3.Immunohistochemistry-Paraffin: GGT1 Antibody (1F9) [H00002678-M01] - Analysis of monoclonal antibody to GGT1 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Yeast
Applications WB, ELISA, ICC/IF

10 Publications

Related Genes

Complete Trisomy 18 Syndrome has been researched against:

Related Pathways

Complete Trisomy 18 Syndrome has been linked to:

Related Diseases

Complete Trisomy 18 Syndrome has been studied in relation to diseases such as:

Related PTMs

Complete Trisomy 18 Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Complete Trisomy 18 Syndrome is also known as Edward's Syndrome, Edwards Syndrome, Edwards' Syndrome, Trisomy 18.