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Adrenoleukodystrophy: Disease Bioinformatics

Research of Adrenoleukodystrophy has been linked to Diffuse Cerebral Sclerosis Of Schilder, Peroxisomal Disorders, Zellweger Syndrome, Adrenomyeloneuropathy, Demyelination. The study of Adrenoleukodystrophy has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Adrenoleukodystrophy include Pathogenesis, Transport, Localization, Fatty Acid Beta-oxidation, Fatty Acid Oxidation. These pathways complement our catalog of research reagents for the study of Adrenoleukodystrophy including antibodies and ELISA kits against ABCD1, ABCD2, ABCD3, CHONDRODYSPLASIA, POMC.

Top Research Reagents

We have 2651 products for the study of Adrenoleukodystrophy that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP3-18137
Western Blot: PEX10 Antibody - BSA Free [NBP3-18137] - WB Validation in Rat Tissues. Loading: 15 ug of lysates per lane. Antibodies: PEX10 NBP3-18137, 4 ug/mL, 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10,000 dilution.Immunocytochemistry/Immunofluorescence: PEX10 Antibody - BSA Free [NBP3-18137] - Immunofluorescent analysis of 4% paraformaldehyde-fixed Daudi cells labeling PEX10 with NBP3-18137 at 20 ug/mL, followed by goat anti-rabbit IgG secondary antibody at 1/500 dilution (green) and DAPI staining (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

NBP1-00154
Western Blot: Arylsulfatase A/ARSA Antibody [NBP1-00154] - Western blot analysis of Mouse testes lysate (A) + peptide (B) with antibody at 1 ug/mL and Rat testes lysate (C) + peptide (D) with antibody at 0.3 ug/mL, 35ug protein in RIPA buffer. Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: Arylsulfatase A/ARSA Antibody [NBP1-00154] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing Golgi apparatus staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
H00008443-B01P
Western Blot: GNPAT Antibody [H00008443-B01P] - Analysis of GNPAT expression in transfected 293T cell line by GNPAT polyclonal antibody.  Lane 1: GNPAT transfected lysate(74.8 KDa). Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: GNPAT Antibody [H00008443-B01P] - Analysis of purified antibody to GNPAT on HeLa cell. (antibody concentration 10 ug/ml)

Mouse Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-80577
Western Blot: PEX1 Antibody [NBP1-80577] - Analysis in human cell line AN3-CA.Immunocytochemistry/Immunofluorescence: PEX1 Antibody [NBP1-80577] - Staining of human cell line A-431 shows positivity in vesicles. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

3 Publications
NBP1-86321
Immunohistochemistry-Paraffin: PEX13 Antibody [NBP1-86321] - Staining in human testis and pancreas tissues using anti-PEX13 antibody. Corresponding PEX13 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: PEX13 Antibody [NBP1-86321] - Staining of human colon, kidney, liver and pancreas using Anti-PEX13 antibody NBP1-86321 (A) shows similar protein distribution across tissues to independent antibody NBP2-38204 (B).

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-87258
Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-87258] - Staining in human liver and skeletal muscle tissues using NBP1-87258 antibody. Corresponding ABCD3 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-87258] - Staining of human kidney, liver, skeletal muscle and testis using Anti-ABCD3 antibody NBP1-87258 (A) shows similar protein distribution across tissues to independent antibody NBP2-38199 (B).

Rabbit Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

5 Publications
NBP1-91642
Immunocytochemistry/Immunofluorescence: ABCB6 Antibody [NBP1-91642] - Staining of human cell line U-251 MG shows localization to the Golgi apparatus.Immunohistochemistry-Paraffin: ABCB6 Antibody [NBP1-91642] - Staining of human testis shows cytoplasmic positivity.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NBP2-02554
Western Blot: ACSBG1 Antibody (1D8) [NBP2-02554] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSBG1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSBG1.Immunocytochemistry/Immunofluorescence: ACSBG1 Antibody (1D8) [NBP2-02554] Staining of COS7 cells transiently transfected by pCMV6-ENTRY ACSBG1.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-21601
Western Blot: ABCD4 Antibody [NBP2-21601] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: ABCD4 Antibody [NBP2-21601] - A431 cells were fixed in ice-cold MeOH for 5 min. Green: ABCD4 protein stained by ABCD4 antibody diluted at 1:500. Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-1533
Immunohistochemistry: POMC Antibody [NB100-1533] - Representative confocal images of POMC in POMC-transfected WT and Sel1L-/- N2a cells. White arrows point to POMC-containing secretory granules, while yellow arrows point to perinuclear POMC. KDEL marks the ER. Representative data from at least 2 independent experiments are shown. Image collected and cropped by CiteAb from the following publication (jci.org/articles/view/96420), licensed under a CC-BY license.Flow Cytometry: POMC Antibody [NB100-1533] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

10 Publications
AF3398
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, Raji human Burkitt's lymphoma cell line, HeLa human cervical epithelial carcinoma cell line, NIH-3T3 mouse embryonic fibroblast cell line, A20 mouse B cell lymphoma cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse/Rat Catalase Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3398) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Raji human Burkitt's lymphoma cell line, loaded at 0.2 mg/mL. A specific band was detected for Catalase at approximately 62 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat Catalase Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3398) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC

     3 Reviews

15 Publications
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

807 Publications
8090-ZN


Species Human
Applications EnzAct

7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications
NBP2-46476
Knockdown Validated: ABCD1 Antibody (OTI2C12) [NBP2-46476] - Western blot shows lysates of TIME human endothelial parental cell line and ABCD1 knockout (KO) TIME cell line. PVDF membrane was probed with 1:2000 of Mouse Anti-Human ABCD1 Monoclonal Antibody (Catalog # NBP2-46476) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog #HAF018). Specific band was detected for ABCD1 at approximately 75 kDa (as indicated) in the parental TIME cell line, but is not detectable in the knockout TIME cell line. This experiment was conducted under reducing conditions.Western Blot: ABCD1 Antibody (OTI2C12) [NBP2-46476] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCD1.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-92633
Immunocytochemistry/Immunofluorescence: ABCD2 Antibody [NBP2-92633] - Analysis of L929 cells using ABCD2 . Blue: DAPI for nuclear staining.Immunocytochemistry/Immunofluorescence: ABCD2 Antibody [NBP2-92633] - Analysis of U-2 OS cells using ABCD2 . Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP3-05516
Immunohistochemistry-Paraffin: FATP2/SLC27A2 Antibody [NBP3-05516] - Staining of human Skeletal muscle shows no positivity in myocytes as expected.Immunohistochemistry-Paraffin: FATP2/SLC27A2 Antibody [NBP3-05516] - Staining of human kidney shows high expression.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P


Related Genes

Adrenoleukodystrophy has been researched against:

Related PTMs

Adrenoleukodystrophy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Adrenoleukodystrophy is also known as adrenoleukodystrophy, x-linked adrenoleukodystrophy, diffuse sclerosis, ald, diffuse cerebral sclerosis of schilder, encephalitis periaxialis concentrica, encephalitis periaxialis, schilder's, sudanophilic cerebral sclerosis, siemerling-creutzfeldt disease, balo's concentric sclerosis, ald (adrenoleukodystrophy), schilder-addison complex, bronze schilder disease, adrenomyeloneuropathy, schilder's disease, schilder disease, leukodystrophies, leukodystrophy.