ZFYVE27 Products

Description

ZFYVE27 is a gene that codes for a protein with eight isoforms, with lengths of 411, 404, 416, 285, 318, 286, 311, and 372 amino acids and weights of approximately 46, 45, 46, 31, 35, 32, 35, and 41 kDa respectively. ZFYVE27 is an upstream inhibitor of RAB11, which regulates directional protein transport to the forming neurites, meaning it is involved in nerve growth factor-induced neurite formation. Current research is being done on several diseases and disorders related to this gene including paraplegia, spasticity, cholangiocarcinoma, and Alzheimer's disease. ZFYVE27 has also been shown to have interactions with VAPA, VAPB, FKBP8, RAB11A, and CCT3.

Bioinformatics

Entrez	118813 Human
Uniprot	NM_144588 Human Q5T4F4 Human
Product By Gene ID	118813
Alternate Names	FLJ32919 PROTRUDIN RP11-459F3.2 SPG33 zinc finger FYVE domain-containing protein 27 zinc finger, FYVE domain containing 27