Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.
Bioinformatics
Entrez |
Rat Human Mouse |
Uniprot |
Human Rat Human |
Product By Gene ID |
57030 |
Alternate Names |
- BNPIbrain-specific Na-dependent inorganic phosphate cotransporter
- Brain-specific Na(+)-dependent inorganic phosphate cotransporter
- member 7
- solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)
- Solute carrier family 17 member 7
- VGluT1
- VGLUT1vesicular glutamate transporter 1
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