Species: Hu, Mu, Rt, Po, Bv, Rb, RM
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. Expressed in all tissues examined. Consists mainly of membrane spanning sided beta sheets. Belongs to the eukaryotic mitochondrial porin family.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
7417 |
| Alternate Names |
- FLJ23841
- hVDAC2
- Outer mitochondrial membrane protein porin 2
- POR
- VDAC-2
- voltage-dependent anion channel 2
- voltage-dependent anion-selective channel protein 2
|
Research Areas for VDAC2
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
