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Urocortin Products

Antibodies
Urocortin Antibody (749606)
Urocortin Antibody (749606)
MAB7447
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Urocortin Antibody (2D7)
Urocortin Antibody (2D7)
NBP2-62804
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
ELISA Kits
Human Urocortin - Ready-To-U ...
Human Urocortin - Ready-To-Use EL...
NBP3-38815
Species: Hu
Applications: ELISA
Human Urocortin ELISA Kit (Co ...
Human Urocortin ELISA Kit (Colorim...
NBP3-38816
Species: Hu
Applications: ELISA

Description

Urocortins 1, 2 and 3 are the mammalian homologs of fish urotensin I. Mammalian urocortin is a member of the corticotropin-releasing hormone(CRH) family that is expressed in a region of the rat midbrain. The distinct expression pattern in discrete brain regions suggests that it influences such behavior as feeding, anxiety and auditory processing. Synthetic human urocortin binds with high affinity to CRH receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells. It is suggested that urocortin may be an endogenous CRF-like factor in the brain responsible for the effects of stress on appetite. The gene which encodes urocortin maps to human chromosome 2. Specifically, urocortin III is a specific ligand for CRF type 2 receptor which mediates stress-coping responses. Human urocortin I and III are expressed in the human heart. Urocortin III is also expressed in the pituitary gland, adrenal gland, GI tract, ovary, spleen, brain and kidney.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Product By Gene ID 7349
Alternate Names
  • MGC129974
  • MGC129975
  • urocortin
  • urocortin, preproprotein
  • UROCUI