TULP3 Products

Description

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Bioinformatics

Entrez	7289 Human
Uniprot	AAH32587 Human AAH32587.1 Human NM_003324 Human
Product By Gene ID	7289
Alternate Names	MGC45295 tubby like protein 3 tubby-related protein 3 TUBL3Tubby-like protein 3

Research Areas for TULP3

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Related TULP3 Blog Posts

Check out the latest blog posts on TULP3.

Can Tubby Make You Tubby? The TUB gene, which encodes for the protein Tubby, is evolutionarily conserved in human, chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, C. elegans, and rice. The gene derives its name from its role in metabolism; mice with a m...    Read more.

Read more TULP3 related blogs.