TRBP Products

Description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Bioinformatics

Entrez	21357 Mouse 363006 Rat 6895 Human
Uniprot	AAB50581 Human AAH05860 Human NP_599150 Human NP_599150.1 Human NP_599151 Human Q15633 Human Q8WY33 Human
Product By Gene ID	6895
Alternate Names	LOQS RISC-loading complex subunit TARBP2 TAR (HIV) RNA binding protein 2 TAR (HIV) RNA-binding protein 2 TAR (HIV) RNA-binding protein TRBP1 TAR (HIV-1) RNA binding protein 2 TAR RNA binding protein 2 TAR RNA-binding protein 2 trans-activation responsive RNA-binding protein Trans-activation-responsive RNA-binding protein TRBP TRBP1 TRBP2