TLR1 Products

Description

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

Bioinformatics

Entrez	228012 Mouse 305354 Rat 7096 Human
Uniprot	CAG38593 Human NM_003263 Human NP_003254 Human NP_003254.2 Human Q15399 Human
Product By Gene ID	7096
Alternate Names	CD281 antigen CD281 DKFZp547I0610 DKFZp564I0682 KIAA0012MGC126311 MGC104956 MGC126312 rsc786 TIL TIL. LPRS5 Toll/interleukin-1 receptor-like protein toll-like receptor 1

Research Areas for TLR1

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Signal Transduction
Toll-Like Receptors

Related TLR1 Blog Posts

Check out the latest blog posts on TLR1.

The role of STING/TMEM173 in gamma and encephalitis Herpes Simplex Virus (HSV) Stimulator of interferon genes (STING), also known as TMEM173, promotes the production of the interferon’s IFN-alpha and IFN-beta.  STING possesses three functional domains: a cytoplasmic C-terminal tail, a central globular domain, and four N-...    Read more.

TLR1 TLR1 belongs to the Toll-like receptor (TLR) family, and is a key player in the recognition of pathogens as well as the activation of the innate immunity system. TLRs are highly conserved proteins with a high degree of structural and functional homolo...    Read more.

Toll-like receptor 2 activation contributes to oral squamous cell carcinoma development and miRNA-mediated drug resistance By Jamshed Arslan, Pharm. D., PhD. Squamous cell carcinoma is the most common cancer in the oral cavity.1 The tumor surface biofilms in oral cancers contain high levels of aerobic and anaerobic microorganisms.1,2 Peri...    Read more.

Read more TLR1 related blogs.