Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Mu
Applications: WB, ELISA, IP, KD
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
SEPHS2 encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
22928 |
Alternate Names |
- EC 2.7.9.3
- Selenophosphate synthase 2
- selenophosphate synthetase 2
- SPS2water dikinase 2
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