Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP, GS
Species: Hu
Applications: AC
Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
861 |
| Alternate Names |
- Acute myeloid leukemia 1 protein
- AML1acute myeloid leukemia 1
- AML1-EVI-1
- CBFA2acute myeloid leukemia 1 protein (oncogene AML-1), core-binding factor, alphasubunit10AMLCR1
- Core-binding factor subunit alpha-2
- EVI-1
- PEBP2A2
- runt domain, alpha subunit 2
- runt-related transcription factor 1
- SL3/AKV core-binding factor alpha B subunit
|
