RIG-I Products

Description

RIG-I, also known as DDX58, consists of a 106.6 kDa and a 101.4 kDa isoform and is involved in recognizing viruses and activating a response. Current research is being conducted with diseases and disorders such as hepatitis, rubella, influenza, rabies, hemorrhagic fever, lupus nephritis, and tick-borne encephalitis. The protein interacts in pathways such as NF-kappa signaling, cytosolic DNA-sensing, measles, influenza A, and mediated induction pathways with proteins such as CYLD, ZC3HAV1, DDX3X, MAVS, and WRNIP1.

Bioinformatics

Entrez	23586 Human
Uniprot	NM_014314 Human NP_055129 Human NP_055129.2 Human O95786 Human
Product By Gene ID	23586
Alternate Names	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 DEAD box protein 58 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide DKFZp686N19181 EC 3.6.4.13 FLJ13599 probable ATP-dependent RNA helicase DDX58 retinoic acid inducible gene I Retinoic acid-inducible gene 1 protein Retinoic acid-inducible gene I protein RIG-1 RIG-IDKFZp434J1111 RNA helicase RIG-I

Research Areas for RIG-I

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Phospho-Specific

Related RIG-I Blog Posts

Check out the latest blog posts on RIG-I.

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Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...    Read more.

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