RCAN1 Products

Description

RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. RCAN1 is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for RCAN1.

Bioinformatics

Entrez	1827 Human 54720 Mouse
Uniprot	AAH02864 Human NP_004405 Human NP_004405. Human NP_981962 Human NP_981962.1 Human NP_981963 Human P53805 Human Q9JHG6 Mouse
Product By Gene ID	1827
Alternate Names	Adapt78 ADAPT78 calcipressin-1 calcium and oxidant-inducible mRNA Down syndrome candidate region 1 Down syndrome critical region gene 1 Down syndrome critical region protein 1 DSC1 modulatory calcineurin-interacting protein 1 Myocyte-enriched calcineurin-interacting protein 1 near DSCR proline-rich protein regulator of calcineurin 1CSP1DSCR1MCIP1RCN1

Research Areas for RCAN1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Neuroscience
Signal Transduction