Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: PAGE
Description
RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. RCAN1 is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for RCAN1.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human Human Human Human Mouse |
Product By Gene ID |
1827 |
Alternate Names |
- Adapt78
- ADAPT78
- calcipressin-1
- calcium and oxidant-inducible mRNA
- Down syndrome candidate region 1
- Down syndrome critical region gene 1
- Down syndrome critical region protein 1
- DSC1
- modulatory calcineurin-interacting protein 1
- Myocyte-enriched calcineurin-interacting protein 1
- near DSCR proline-rich protein
- regulator of calcineurin 1CSP1DSCR1MCIP1RCN1
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