RBM8A Products

Description

Pre-mRNA splicing appears to play an important role in regulation of gene expression. It has been shown in a number of studies that during the splicing process, specific proteins are recruited to the mRNA and assemble into a complex of mRNA-protein near the exon-exon junction. This complex is termed mRNA-protein complex (mRNP), or the exon-exon junction complex. Several proteins were found to be present in this complex including Y14, magoh, Aly/REF, RNPS1, Upf3, and DEK. Y14 is a 174 amino acid RNA-binding protein that contains one RNA-binding domain in the middle of the protein. Y14 binds to the spliced mRNAs in the nucleus and is exported with the mRNA to the cytoplasm. Similar to other proteins in the mRNA-protein complex, Y14 can interact with the mRNA export factor TAP and enhance the export of the mRNAs. Y14 binds to different mRNAs approx.

Bioinformatics

Entrez	60365 Mouse 9939 Human
Uniprot	AAH17088 Human NM_005105 Human NP_005096 Human NP_005096.1 Human Q9Y5S9 Human
Product By Gene ID	9939
Alternate Names	Binder of OVCA1-1 BOV-1 BOV-1A BOV-1B BOV-1C MDS014 RBM8BRBM8 ribonucleoprotein RBM8 Ribonucleoprotein RBM8A RNA binding motif protein 8A RNA binding motif protein 8B RNA-binding motif protein 8A RNA-binding protein 8A RNA-binding protein Y14 Y14 ZNRP ZRNP1