PPFIBP1 Products

Description

PPFIBP1 is encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longer isoform (1).

Bioinformatics

Entrez	8496 Human
Uniprot	NM_003622 Human NP_803193 Human Q86W92 Human Q86W92-5 Human
Product By Gene ID	8496
Alternate Names	hSGT2liprin related protein hSgt2p KIAA1230 L2 liprin-beta 1 liprin-beta-1 Protein tyrosine phosphatase receptor type f polypeptide-interactingprotein-binding protein 1 protein-tyrosine phosphatase receptor-type f polypeptide-interactingprotein-binding protein 1 PTPRF interacting protein, binding protein 1 (liprin beta 1) PTPRF-interacting protein-binding protein 1 SGT2