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POLR1B Products

Antibodies
POLR1B Antibody (4H6)
POLR1B Antibody (4H6)
H00084172-M10
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
POLR1B Antibody - Azide and B ...
POLR1B Antibody - Azide and BSA Free
NBP2-93757
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
POLR1B Antibody
POLR1B Antibody
NBP1-53191
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
POLR1B Overexpression Lysate
POLR1B Overexpression Lysate
NBL1-14574
Species: Hu
Applications: WB

Description

POLR1B, also known as DNA-directed RNA polymerase I subunit RPA2, has a 1,135 amino acid long isoform that is approximately 128kDa, and a short 1,079 amino acid isoform that is approximately 121kDa. POLR1B is a RNA polymerase that is localized to the nucleolus. POLR1B is the second largest fundamental element of pol I, which is responsible for the production of ribosomal RNA. Current research on POLR1B is being performed in relation to several diseases and disorders including pneumonia, malaria and tuberculosis. POLR1B has also been shown to have interactions with Histone cluster 1 H4/A, H4/B, H4/C, H4/D and H4/E in pathways such as RNA Polymerase I transcription and RNA Polymerase III transcription.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 84172
Alternate Names
  • DNA-directed RNA polymerase I 135 kDa polypeptide
  • DNA-directed RNA polymerase I 135kDa polypeptide
  • DNA-directed RNA polymerase I subunit RPA2
  • EC 2.7.7.6
  • FLJ10816
  • FLJ21921
  • MGC131780
  • polymerase (RNA) I polypeptide B, 128kDa
  • RNA polymerase I subunit 2
  • RPA116
  • RPA135
  • RPA2
  • Rpo1-2