Plastin L Products

Description

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. (provided by RefSeq)

Bioinformatics

Entrez	3936 Human
Uniprot	NM_002298 Human P13796 Human
Product By Gene ID	3936
Alternate Names	CP64 DKFZp781A23186 FLJ25423 FLJ26114 FLJ39956 LC64PPLS2bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)) LCP-1 LPL L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P) L-PLASTIN L-plastin lymphocyte cytosolic protein 1 (L-plastin) Lymphocyte cytosolic protein 1 Lymphocyte cytosolic protein-1 (plasmin) plastin 2 plastin-2