PKLR Products

Description

The protein encoded by the Pyruvate Kinase gene is a pyruvate kinase that catalyzes the transphosphorylation of phosphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Bioinformatics

Entrez	5313 Human
Uniprot	AAH25737 Human NM_000298 Human NP_000289 Human NP_000289.1 Human P30613 Human P30613-2 Human
Product By Gene ID	5313
Alternate Names	EC 2.7.1.40 PK1PKRL PKL PKR Pyruvate kinase 1 pyruvate kinase isozyme R/L pyruvate kinase isozymes R/L pyruvate kinase type L pyruvate kinase, liver and blood cell pyruvate kinase, liver and RBC Red cell/liver pyruvate kinase RPK R-type/L-type pyruvate kinase

Research Areas for PKLR

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Signal Transduction