PIP5K2 gamma Products

Description

PIP5K2 also known as Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, has 3 isoforms, a 421 amino acid isoform that is 47 kDa, a 373 amino-acid isoform that is 42 kDa and a 403 amino-acid isoform that is 45 kDa; mostly found in the cytosol and surrounding plasma membrane; may be important in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum. Disease research is currently being studied with relation to PIP5K2 and rheumatoid arthritis and arthritis. This protein has interactions with BTK, STK11, PIP4K2C, PIK3CG, PIK3R3, PIP5K1A, and over 40 other proteins in D-myo-inositol-5-phosphate metabolism, regulation of actin cytoskeleton, B cell Receptor signaling pathway, D-myo-inositol (1,4,5)-trisphosphate biosynthesis, superpathway of inositol phosphate compounds, inositol phosphate metabolism, and phosphatidylinositol signaling system pathways.

Bioinformatics

Entrez	79837 Human
Uniprot	NM_024779 Human NP_079055 Human Q8TBX8 Human
Product By Gene ID	79837
Alternate Names	EC 2.7.1 EC 2.7.1.149 FLJ22055 phosphatidylinositol-4-phosphate 5-kinase, type II, gamma Phosphatidylinositol-5-phosphate 4-kinase type II gamma phosphatidylinositol-5-phosphate 4-kinase type-2 gamma phosphatidylinositol-5-phosphate 4-kinase, type II, gamma PI(5)P 4-kinase type II gamma PIP4KII-gamma PIP5K2C