PCAF Products

Description

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Bioinformatics

Uniprot	AAH60823 Human NP_003875 Human Q92831 Human
Product By Gene ID	8850
Alternate Names	CREBBP-associated factor EC 2.3.1.48 GCN5L Histone acetylase PCAF histone acetyltransferase KAT2B Histone acetyltransferase PCAF K(lysine) acetyltransferase 2B Lysine acetyltransferase 2B P P/CAFGCN5 P300/CBP-associated factorCAF PCAF

Research Areas for PCAF

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Chromatin Research
HIF Target Genes
Hypoxia
Membrane Trafficking and Chaperones
Signal Transduction
Transcription Factors and Regulators