Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition ofmultiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to glu/asp residues onthe substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. PARP inhibitors are beingdeveloped for use in a number of pathologies including cancer, diabetes, stroke and cardiovascular disease.
Bioinformatics
Uniprot |
Human |
Product By Gene ID |
64761 |
Alternate Names |
- EC 2.4.2.30
- FLJ22693MST109
- PARP-12
- poly (ADP-ribose) polymerase family, member 12
- poly [ADP-ribose] polymerase 12
- ZC3H1
- ZC3HDC1MSTP109
- Zinc finger CCCH domain-containing protein 1
- zinc finger CCCH type domain containing 1
- zinc finger CCCH-type domain containing 1
|
Research Areas for PARP12
Find related products by research area and learn more about each of the different research areas below.
DNA RepairHypoxia