Noggin Products

Description

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Bioinformatics

Uniprot	AAA83259.1 Human AAH34027 Human NM_005450 Human NP_005441 Human NP_005441.1 Human Q13253 Human
Product By Gene ID	9241
Alternate Names	noggin SYM1 symphalangism 1 (proximal) synostoses (multiple) syndrome 1 SYNS1

Research Areas for Noggin

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Stem Cell Markers
Stem Cell Signaling Pathway