Species: Hu, Mu, Rt, Po, Bv, Ch, Dr, Eq
Applications: WB, ICC/IF, IHC, IHC, KD
Host: Chicken Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ch, Eq
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ch, Eq
Applications: WB, ICC/IF, IHC, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Neurofilaments are 10nm intermediate filament proteins located in vertebrate neurons, which regulate axonal diameter. They are composed predominantly of the three major neurofilament proteins: NF-Light, NF-Medium and NF-Heavy. NF-M is the middle or medium neurofilament subunit and runs on SDS-PAGE gels in the range 145-170kDa, with some size variation in across species.
Antibodies to NF-M may be used to identify NF-M in neurons and to study neuronal processes in tissue sections and/or culture. NF-M can also be useful in studies of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Rat
|
| Product By Gene ID |
4741 |
| Alternate Names |
- NEF3neurofilament medium polypeptide
- Neurofilament 3
- neurofilament, medium polypeptide 150kDa
- neurofilament, medium polypeptide
- neurofilament-3 (150 kD medium)
- NF-M160 kDa neurofilament protein
- NFMNeurofilament triplet M protein
|
