Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
![Western Blot Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin-2_AF2229_Western_Blot_9317.jpg)
![Sandwich ELISA Nectin-2/CD112 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Nectin-2-CD112-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79431-img0001.jpg)
![N/A Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/dy2229-05_human-nectin-2-cd112-duoset-elisa-5-plate-2522022102954.jpg)
![Binding Activity Nectin-2/CD112 [Unconjugated]](http://images.novusbio.com/fullsize/protein/10617-n2_recombinant-cynomolgus-monkey-nectin-2-cd112-his-protein-cf-binding-activity-312202010658.jpg)
![Binding Activity Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi9317_recombinant-human-nectin-2-cd112-fc-avi-tag-protein-cf-binding-activity-1912022123048.jpg)
![Binding Activity Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi2229_recombinant-human-nectin-2-cd112-his-tag-avi-tag-protein-cf-binding-activity-2012022103035.jpg)
![Immunocytochemistry Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Immunocytochemistry__Immunofluorescence_21146.jpg)
![Immunohistochemistry Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Immunohistochemistry_21147.jpg)
![Simple Western Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Simple_Western_21749.jpg)
![Western Blot Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af2229_human-nectin-2-cd112-affinity-purified-polyclonal-ab-4120241240231.jpg)
![SDS-PAGE Nectin-2/CD112 [Unconjugated]](http://images.novusbio.com/fullsize/protein/10617-n2_recombinant-cynomolgus-monkey-nectin-2-cd112-his-protein-cf-sds-page-219202015719.jpg)
![SDS-PAGE Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi9317_recombinant-human-nectin-2-cd112-fc-avi-tag-protein-cf-sds-page-612202185920.jpg)
![SDS-PAGE Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi2229_recombinant-human-nectin-2-cd112-his-tag-avi-tag-protein-cf-sds-page-2012022104416.jpg)