Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq]
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
4694 |
| Alternate Names |
- CI-MWFEcomplex I MWFE subunit
- Complex I-MWFE
- MWFENADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
- NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE)
- NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- NADH oxidoreductase subunit MWFE
- NADH:ubiquinone oxidoreductase (complex 1)
- NADH-ubiquinone oxidoreductase MWFE subunit
- type I dehydrogenase
- ZNF183
|
