Mxi1 Products

Description

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Bioinformatics

Uniprot	AAH12907 Human NM_001008541 Human NP_001008541 Human NP_001008541.1 Human NP_005953.4 Human NP_569157 Human P50539 Human
Product By Gene ID	4601
Alternate Names	BHLHC11 Class C basic helix-loop-helix protein 11 MAX dimerization protein 2 MAX interacting protein 1 MAX interactor 1bHLHc11MAD2 max-interacting protein 1 Max-related transcription factor MGC43220 MXD2 MXI

Research Areas for Mxi1

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Cell Cycle and Replication