Migfilin Products

Description

FBLIM1 encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Bioinformatics

Entrez	54751 Human
Uniprot	ABM85833.1 Human NM_017556 Human NP_060026 Human Q8WUP2 Human
Product By Gene ID	54751
Alternate Names	CAL DKFZp434G171 FBLP-1FBLP1CSX-associated LIM filamin binding LIM protein 1 filamin-binding LIM protein 1 filamin-binding LIM protein-1 MIG2-interacting protein Migfilin migfilin MIGFILIN mitogen-inducible 2 interacting protein Mitogen-inducible 2-interacting protein