MAP4 Products

Description

MAP4 is encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed, the full-length nature of three of which are supported.

Bioinformatics

Entrez	4134 Human
Uniprot	NP_002366.2 Human NP_112147 Human NP_112147.2 Human P27816 Human
Product By Gene ID	4134
Alternate Names	DKFZp779A1753 MAP-4 MGC8617 microtubule-associated protein 4

Research Areas for MAP4

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Cellular Markers
Phospho-Specific