Lyn Products

Description

Src is the human homolog of the v-Src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family kinases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src-family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. The human Lyn gene maps to chromosome 8q13 and encodes a 505 amino acid protein. Hematopoietic tissues predominantly express Lyn, which influences normal immunoglobulin production and regulation.

Bioinformatics

Entrez	17096 Mouse 4067 Human 81515 Rat
Uniprot	BC059394 Human NM_002350 Human NP_002341 Human NP_002341.1 Human P07948 Human
Product By Gene ID	4067
Alternate Names	EC 2.7.10 EC 2.7.10.2 FLJ26625 JTK8 tyrosine-protein kinase Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog

Research Areas for Lyn

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase
Signal Transduction