Kv7.1 Products

Description

KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described (from EntrezGene).

Bioinformatics

Entrez	16535 Mouse 3784 Human 84020 Rat
Uniprot	NP_000209 Human NP_000209.2 Human NP_861463 Human NP_861463.1 Human P51787 Human
Product By Gene ID	3784
Alternate Names	ATFB3 IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 JLNS1 KCNA8FLJ26167 KCNA9Kv1.9 kidney and cardiac voltage dependend K+ channel KQT-like 1 Kv7.1 KVLQT1ATFB1 LQT LQT1 potassium voltage-gated channel subfamily KQT member 1 potassium voltage-gated channel, KQT-like subfamily, member 1 RWS slow delayed rectifier channel subunit SQT2 Voltage-gated potassium channel subunit Kv7.1 WRS