Intersectin 2 Products

Description

Intersectin-2 is a cytoplasmic adapter protein that may provide a link between the actin assembly machinery and the endocytic membrance traffic, as well a control the production of clathrin-coated vesicles in terms of their invagination of budding. Intersectin-2 has four isoforms, with lengths of 1697, 1670, 1249, and 1192 amino acids and weights of 193, 190, 141, and 135 kDa respectively. Studies have been conducted on diseases and disorders related to this protein including Wiskott-Aldrich syndrome, dermatitis, sarcoma, schizophrenia, spasticity, pancreatitis, and pancreatic cancer. Intersectin-2 has also been known to have interactions with BCCIP, PTN, TBL3, MAP4K3, and SEMA6A in pathways such as the regulation of CDC42 activity pathway.

Bioinformatics

Entrez	50618 Human
Uniprot	NP_006268 Human NP_006268.2 Human
Product By Gene ID	50618
Alternate Names	intersectin 2 KIAA1256SH3 domain-containing protein 1B PRO2015 SH3 domain protein 1B SH3P18-like WASP associated protein SH3P18SH3D1Bintersectin-2 SWA SWAPSH3P18-like WASP-associated protein