IFIT3 Products

Description

IFIT3, also known as IFIT4, IFI60, and RIGG, has been identified as a key element in the IFN-alpha anti-viral pathway. Additionally, IFIT3 binding negatively regulates the apoptotic effects of ISG54. IFIT3 is also a key target of STAT1, which is important in regulating IFN responses. One study has shown that expression of RIGG in a human monocytoma line led to growth arrest at the G1/S transition.

Bioinformatics

Entrez	3437 Human
Uniprot	NM_001031683 Human NM_001549 Human NP_001540 Human NP_001540.2 Human O14879 Human
Product By Gene ID	3437
Alternate Names	CIG-49 GARG-49 IFI60Retinoic acid-induced gene G protein IFIT-3 IFIT-4 IFIT4IFI-60K interferon-induced protein with tetratricopeptide repeats 3 Interferon-induced protein with tetratricopeptide repeats 4Interferon-induced 60 kDa protein IRG2 ISG60 ISG-60 RIG-GCIG49