H4/h Products

Description

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. H4/H is a103 amino acid long, 11 kDA protein encoded by the HIST1H4H gene found on chromosome 6. HIST1H4H is intronless and its proteins lack polyA tails but contain palindromic termination elements. HIST1H4H is active in type II interferon signaling, nucleosome assembly, telomere maintenance, histone modification, and nuclear receptor activation by vitamin-A. It interacts with other genes such as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, and HIST1H3E. the HIST1H4H gene has been investigated for its role in carcinoma, immunodeficiency, lymphoma, and lupus.

Bioinformatics

Entrez	8365 Human
Uniprot	NM_003543 Human NP_003534 Human
Product By Gene ID	8365
Alternate Names	H4 histone family, member H H4/A H4/B H4/C H4/D H4/E H4/H H4/h H4/I H4/J H4/K H4/M H4/N H4/O H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FHH4/G H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4 HIST2H4A HIST2H4B HIST4H4 histone 1, H4h histone cluster 1, H4h histone H4