Grancalcin Products

Description

Grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Bioinformatics

Entrez	25801 Human
Uniprot	AAH05214 Human NM_012198 Human NP_036330 Human P28676 Human
Product By Gene ID	25801
Alternate Names	EF-hand calcium-binding protein grancalcin, EF-hand calcium binding protein grancalcin, penta-EF-hand protein