Species: Hu
Applications: WB, ELISA, Flow, IHC, CyTOF-ready, ICC/IF
Host: Sheep Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, CyTOF-ready, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Binding Activity
Species: Pm-Cm, RM
Applications: Bioactivity
Description
The Glypican 3 (GPC3) gene encodes for a member of the glypican-related integral membrane proteoglycan family (GRIPS). Two isoforms of the protein exist, isoform 1 at a length of 580 amino acids long and 65 kDA while isoform 2 is 526 amino acids long at 59 kDA. The protein encoded by GPC3 is thought to prevent the dipeptidyl peptidase activity of DPP4 and may participate in the suppression and regulation of growth in the predominately mesodermal tissues and organs. The GPC3 gene participates in the Wnt signaling pathway, metabolism, and visual phototransduction through interactions with genes FGF2, WNT3A, WNT7B, BCAN, and BGN. GPC3 has been researched in various diseases such as paine syndrome, horner's sundrome, liver cirrhosis, simpson-golabi-behmel syndrome, germ cell tumors, wilms tumors, complex regional pain syndrome, and hepatocellulcar carcinoma.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
2719 |
| Alternate Names |
- DGSX
- glypican 3
- glypican proteoglycan 3
- glypican-3
- GTR2-2
- heparan sulphate proteoglycan
- Intestinal protein OCI-5
- MXR7
- OCI5
- OCI-5
- secreted glypican-3
- SGB
- SGBS
- SGBS1SDYS
|
![Western Blot Glypican 3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/12878.jpg)
![Western Blot Glypican 3 Antibody (307801) [Unconjugated]](http://images.novusbio.com/fullsize2/Glypican_3_MAB2119_Western_Blot_21501.jpg)
![N/A Glypican 3 [HRP]](http://images.novusbio.com/fullsize2/DATA_Glypican_3_DGLY30_ELISA_702.jpg)
![N/A Glypican 3 [Biotin]](http://images.novusbio.com/fullsize2/DATA_Glypican_3_DY2119_ELISA_1768.jpg)
![Bioactivity Glypican 3 [Unconjugated]](http://images.novusbio.com/fullsize/protein/2119-gpcf_recombinant-human-glypican-3-protein-cf-bioactivity-1412202083058.jpg)
![Bioactivity Glypican 3 [Unconjugated]](http://images.novusbio.com/fullsize/protein/2119-gp_recombinant-human-glypican-3-protein-bioactivity-1412202082934.jpg)
![Binding Activity Glypican 3 [Unconjugated]](http://images.novusbio.com/fullsize/protein/10509-gp_recombinant-cynomolgus-rhesus-glypican-3-his-tag-protein-cf-binding-activity-1162020194345.jpg)
![Immunocytochemistry Glypican 3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Glypican_3_AF2119_Immunocytochemistry__Immunofluorescence_20870.jpg)
![Immunohistochemistry Glypican 3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Glypican_3_AF2119_Immunohistochemistry_6734.jpg)
![Immunohistochemistry Glypican 3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Glypican_3_AF2119_Immunohistochemistry_9762.jpg)
![ELISA Glypican 3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af2119_human-glypican-3-affinity-purified-polyclonal-ab-elisa-1011202010021.jpg)
![Western Blot Glypican 3 Antibody (307801) [Unconjugated]](http://images.novusbio.com/fullsize2/12879.jpg)
![Immunocytochemistry Glypican 3 Antibody (307801) [Unconjugated]](http://images.novusbio.com/fullsize2/Glypican_3_MAB2119_Immunocytochemistry__Immunofluorescence_20869.jpg)
![N/A Glypican 3 [HRP]](http://images.novusbio.com/fullsize2/Glypican_3_DGLY30_ELISA_502.jpg)
