Glutamate Receptor 4 Products

Description

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem, whereas the four epsilon subunits display limited distribution.

Bioinformatics

Entrez	14802 Mouse 268934 Mouse 2893 Human 29629 Rat
Uniprot	NP_000820.3 Human NP_001070712.1 Human P48058 Human
Product By Gene ID	2893
Alternate Names	AMPA-selective glutamate receptor 4 GluA4 GluR4 GluR-4 gluR-4 GLUR4C GLUR4gluR-D GLURD GluR-D glutamate receptor 4 Glutamate receptor ionotropic, AMPA 4 glutamate receptor, ionotrophic, AMPA 4